How does Joel know they could make a cure?

The Fireflies don’t look particularity competent, and get both in the show and the game Joel apparently has zero doubt they can do it

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They were going to make a cure but that doesn't mean the cure itself would actually work.

The cure is a retcon. In the original game (created by Bruce Straley, who was forced out) it wasn’t possible.

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Why couldn’t they just do a blood draw?

how would they even distribute the cure?
through how many clinical trials would this shit have to go before they can be sure it works?
without proper logistics the cure is pointless

Why does reddit have better info than us? They're supposed to be posting our screencaps

Because frankly we’re retarded and stop researching as soon as we’ve rushed to conclusions

still seething about an ambiguous ending 12 yesrs later

TLOU brainlets who wanted a sequel deserved to watch Joel die

They needed brain matter or something form what I recall. Might remember wrong, it was over decade ago

That’s old hat.
Anon Babble says Amy Hennig was the true mastermind now

this is the interview from 2013 with both Bruce and Neil.

Ultimately, at least for Joel, it became this idea of exploring how far a father is willing to go to save his kid. Each step of the way is a greater sacrifice. At first, he’s willing to put his life on the line. That’s almost the easiest thing for him, where he’s at. But then he’s willing to put his friends on the line. Finally it comes to putting his soul on the line, when he’s willing to damn the rest of humanity. When he has that final lie with Ellie, he’s willing to put his relationship with Ellie on the line in order to save her.

i guess Bruce kinda forgot the cure wasn't possible and didn't correct Neil here

Its not a retcon if it was cut before release.

ambiguous

neil already said the cure would have worked and that joel just doomed humanity, there is nothing ambiguous about it anymore

first of all it never was ambigous. Also, people who say it was ambigous at the same time say they would never make it so it's just another schizochudism

He didn't need to know for sure. He just believed it.

3rd year med student here. Nothing the Fireflies were intending to do suggests they had any idea what they were doing. Though, I assume that's just because Naughty Dog writers didn't consult any medical professionals, not necessarily because they were supposed to seem entirely incompetent? Hard to say.

Realistically they would need to develop a gene treatment rather than a cure or a vaccine, unless they had made huge advances in the treatment of fungal infections in general, which doesn't seem likely in a post-apocalyptic world.

It was the fungus in Ellie's brain that had mutated and made her immune.
They didn't give a medical reason for why they needed to kill her and remove the whole thing in order to create the vaccine, rather than just do a minimally invasive biopsy... or for how they knew that's where her immunity stemmed from, without having done it already

This is just wrong. Nothing here was retconned. It was always obvious that Joel's choice was made even with the knowledge it could doom humanity. Thats literally what makes the idea of the story work in the first place.

Bruce didn't contribute any writing to the script. Neil did all of that. BUT Bruce did contribute ideas for the script.
Even so this image is objectively wrong about Bruce being forced out.
Neil has always been completely candid about TLOU being a group project. That he isn't an Auteur, etc.
But even so only the people who produced the work gets credited for it, and Neil is credited solely as the writer.

It was always obvious that Joel's choice was made even with the knowledge it could doom humanity

Joel very well could have believed that but the game didn't do a very good job of making the players believe it. That's the problem.

I don't think you need to be a medical professional to realize that an insane dirty hobo lookin "doctor" who plays sawbones for a mad max style gang of psychos working in a dirty basement with a dentist's chair wasn't going to succeed in creating a vaccine for the mushroom zombie virus by cutting the brain out of somebody immune to it. Also even if those mad max psychos somehow magically turned Ellie's brain in to a vaccine it's not like they had facilities to produce more of it. And even if they somehow magically COULD make a vaccine, they would have just used it as leverage to try to take over the world or something.
Also thematically, the entire point of the ending is that Ellie wakes up in this nasty dump with the realization that the people who were "totally going to make a cure" were actually nutcases who were going to murder her in a filthy basement, there's not going to be a cure, the world isn't going to just get better, and all she can hope for is to survive in this ruined hellscape. This is directly juxtaposed with Joel realizing his new surrogate daughter Ellie has become his reason to live.
In conclusion: NEXT GUY NEXT GUY

She has a brain tumor that produces pheromones fooling the fungi. Cancer cells are extremely easy to replicate because they can multiplication forever unlike normal human cells with built-in expire date. That's what makes them so deadly, because your body have to feed all that extra cells. There's that one dude who died like 50 years ago but labs keep using his cancer cells in experiments. His combined body tissue weigh is something like two tonnes by now.
The docror in tlou planned to do the same with her tumor and just grow it in-vtro and inject everybody with the pheromone so fungus ignores them.

Ellie wakes up in this nasty dump with the realization that the people who were "totally going to make a cure" were actually nutcases who were going to murder her in a filthy basement

That's not how she feels about it at all. She's on board with it. Did you play the game?

Ellie wakes up in this nasty dump

What? She wakes up in the back seat of the car Joel stole, as they are on their way back to what might be the least-nasty place in the world

Also thematically, the entire point of the ending is that Ellie wakes up in this nasty dump with the realization that the people who were "totally going to make a cure" were actually nutcases who were going to murder her in a filthy basement, there's not going to be a cure, the world isn't going to just get better, and all she can hope for is to survive in this ruined hellscape

you really think that's thematically the point of the ending?

chuds hallucinating even more things about last of us

reposting

moral quandary so strong people are retconning it in their heads because it makes them uncomfortable

they are hallucinating audiologs out of thin air

they are desperately fighting it for literal years

we're talking about a videogame

neil druckmann is a god tier writer

most gamers have a mind of a child is what I've noticed.

Th original game left it up in the air, you find files of firefly scientist saying they are close to a cure and you also find files of fireflies members talking about how many times they failed and how they will probably fail again.

The original game left it up in the air

that was the beauty of the ending but cuckmanns could not ignore his ego and hate for white men/christians and had to fuck up.. he was the wrong pick to direct a sequel on top of that to a game that didnt even need a sequel because it had a perfect ending

hate for white men/christians

If somehow the Lord gave me another shot at that moment, I would do it all over again

^which is the most powerful line delivery in the game and invokes even more respect and admiration from the player even if Ellie disagrees with it

It wasn’t really ambiguous, and it would have made Joel less appealing if he’d doubted the cure was possible and that factored into his decision. It didn’t. He just loved Ellie. I don’t know why people who worship Joel need to believe the cure might not have worked. He did what any father would do; Druckmann said he’d do the same.
And according to the logs they’d never found any cases of true immunity before.

It’s weird that he made Joel white and Christian, and Sarah and Ellie white too if he hates white Christians so much. He really didn’t have to.

The point is you dont know (although leaning towards no, because they already done it befored and it failed).

This is what I'm talking about:
en.m.wikipedia.org/wiki/HeLa
Fireflies hoped they can cultivate that special tumor in labs and make them produce the thing that made fungus ignore Ellie's body.

Safe and effective

Would it be "possible"? Or just another "at least we tried" empty attempt

Even if her having a brain tumor was true in the games or at some point in the writing process for them, it wouldn't apply to the show where Ellie is immune due to the stupid umbilical cord thing.

It could have been a neat way to end the trilogy in Part 3, have her find out she's dying from the tumor and see how this impacts her life choices... but it's probably not part of Druck's plan now

thats kinda retarded, if you have a possibility for a literal once in a humanity saving cure you give it a try no matter if the success rate is very low

through how many clinical trials would this shit have to go before they can be sure it works?

Ten unlucky POVs followed by 100 volunteers and whoever happens to get bitten in meantime.

how would they even distribute the cure?

Announcements on shortwave radio. Mass vaccination events in city squares at trade points. Armed convoys transporting new batches to nearby cities. Establishing technical schools that teach how to cultivate the vaccine -producing bacteria / cells and separate the cure. Establishing vaccinated cleanup columns that travel the main roads setting any potential fungi colony on fire.

TLOU 2 was made as a giant "fuck you" to fans of the first because Druckmann didn't have full control over the former.

Maybe the trial subjects wouldn't be that unlucky... a non-immune person can still inhale a few spores without getting infected, right?
So just puff a low dose of spores in their face and see if it makes them cough or not

the author said

Who cares